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Time-dependent metabolomics uncover dynamic metabolic adaptions in MCF-7 cells exposed to bisphenol A

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 1, doi: 10.1007/s11783-023-1604-5

Abstract:

● Metabolomic temporal profiling of cells exposed to xenobiotics.

Keywords： Metabolomics     BPA     MCF-7     Temporal profiling     Metabolic adaption     Dysregulation correlation    

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Epigenetic dysregulation in hepatocellular carcinoma: focus on polycomb group proteins

Sandy Leung-Kuen Au, Irene Oi-Lin Ng, Chun-Ming Wong

Frontiers of Medicine 2013, Volume 7, Issue 2,   Pages 231-241 doi: 10.1007/s11684-013-0253-7

Abstract:

Hepatocellular carcinoma (HCC) development is characterized by the presence of epigenetic alterations, including promoter DNA hypermethylation and post-translational modifications of histone, which profoundly affect expression of a wide repertoire of genes critical for cancer development. Emerging data suggest that deregulation of polycomb group (PcG) proteins, which are key chromatin modifiers repressing gene transcription during developmental stage, plays a causative role in oncogenesis. PcG proteins assemble into polycomb repressive complex 1 (PRC1) and polycomb repressive complex 2 (PRC2) to impose the histone H3 lysine 27 trimethylation (H3K27me3) modification for repression. In this review, we will first recapitulate the mechanisms of two key epigenetic pathways: DNA methylation and histone modifications. Specifically, we will focus our discussion on the molecular roles of PcG proteins. Next, we will highlight recent findings on PcG proteins, their clinicopathological implication and their downstream molecular consequence in hepatocarcinogenesis. Last but not least, we will consider the therapeutic potential of targeting enhancer of zeste homolog 2 (EZH2) as a possible treatment for HCC. Improving our understanding on the roles of PcG proteins in hepatocarcinogenesis can benefit the development of epigenetic-based therapy.

Keywords： liver cancer     epigenetics     histone modifications     polycomb group proteins     enhancer of zeste homolog 2 (EZH2)    

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Digital image correlation-based structural state detection through deep learning

Frontiers of Structural and Civil Engineering 2022, Volume 16, Issue 1,   Pages 45-56 doi: 10.1007/s11709-021-0777-x

Abstract: The digital image correlation (DIC) technology was utilized to collect vibration information of an actual

Keywords： structural state detection     deep learning     digital image correlation     vibration signal     steel frame    

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Diagnosis method based on wavelet coefficient scale relativity correlation dimension for fault

GU Junjie, TIAN Jin, PENG Xuezhi

Frontiers in Energy 2008, Volume 2, Issue 2,   Pages 164-168 doi: 10.1007/s11708-008-0031-4

Abstract: Correlation dimension as a tool to describe machinery condition is introduced.The correlation dimension is able to identify conditions of the fan with faults compared with the normal

Keywords： effective technology     monitoring     mechanical equipment     relativity     Correlation    

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Reliability analysis of urban gas transmission and distribution system based on FMEA and correlation

Su LI,Weiguo ZHOU

Frontiers in Energy 2014, Volume 8, Issue 4,   Pages 443-448 doi: 10.1007/s11708-014-0336-4

Abstract: To solve the problem of subjectivity and uncertainty of the multi-expert decision making, the correlationThe results show that correlation operator can directly process the linguistic terms and quantify the

Keywords： and distribution system     risk evaluation     reliability analysis     failure mode and effects analysis (FMEA)     correlation    

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Measurement and correlation of the solid-liquid equilibrium of 2-(

Yanhong SUN, Zhiyong LI, Chuang XIE, Wei CHEN, Cui ZHANG

Frontiers of Chemical Science and Engineering 2013, Volume 7, Issue 1,   Pages 110-115 doi: 10.1007/s11705-013-1316-7

Abstract: In this work, the enthalpy of fusion and melting points of 2-( -butyl)-5-methylphenol (2B5MP) and 2-( -butyl)-4-methylphenol (2B4MP) were measured by differential scanning calorimetry (DSC). The binary solid-liquid equilibrium (SLE) of both compounds were predicted by integrated computer aided system (ICAS) and measured by DSC. The corresponding eutectic molar composition is 0.6998 and the eutectic temperature is 281.96 K. The quasi-static heat capacities of 2B5MP and 2B4MP were evaluated by stochastic temperature modulation DSC technique (TOPEM). The SLE experimental data were correlated using the Margules, Wilson, and non-random two liquid (NRTL) equations and a good agreement between measurement and calculation could be obtained.

Keywords： solid-liquid equilibrium (SLE)     eutectic     integrated computer aided system (ICAS)     TOPEM     correlation    

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Deformation field and crack analyses of concrete using digital image correlation method

Yijie HUANG, Xujia HE, Qing WANG, Jianzhuang XIAO

Frontiers of Structural and Civil Engineering 2019, Volume 13, Issue 5,   Pages 1183-1199 doi: 10.1007/s11709-019-0545-3

Abstract: distribution and crack propagation of concrete under axial compression was conducted by the digital image correlation

Keywords： deformation filed distribution     crack development     digital image correlation method     mechanical properties    

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Free radical scavenging window of infertile patients with polycystic ovary syndrome: correlation with

Bo Huang, Zhou Li, Xinling Ren, Jihui Ai, Lixia Zhu, Lei Jin

Frontiers of Medicine 2017, Volume 11, Issue 2,   Pages 247-252 doi: 10.1007/s11684-017-0519-6

Abstract:

The activity of free radicals in follicular fluid was related to ovarian responsiveness, in vitro fertilization (IVF), and embryo transfer success rate. However, studies analyzing the relationship between the free radical scavenging capacity and embryo quality of infertile women with polycystic ovarian syndrome (PCOS) were lacking. The aim of this study was to evaluate the relationship between the free radical scavenging window of women with PCOS and their embryo quality. The free radical scavenging capacity of follicular fluid from women with PCOS was determined by a,a-diphenyl-b-picrylhydrazyl (DPPH), 2,2-azinobis (3-ethylbenzthiazoline-6-sulphonic acid) assay, superoxide radical, and reactive oxygen species (ROS) assay. In the DPPH and ROS assays, the follicular fluid from grades I and II embryos was significantly higher than the follicular fluid from grades III and IV embryos. The lower control limit of DPPH radical scavenging capacity and upper control limit of ROS level were 13.2% and 109.0 cps, respectively. The calculated lower control limit and upper control limit were further confirmed in the follicular fluid of embryos of all grades. These cut-off values of free radical scavenging activity of follicular fluid could assist embryologists in choosing the development of embryos in PCOS patients undergoing IVF.

Keywords： in vitro fertilization     PCOS     free radical     embryo quality    

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Characteristic and correlation analysis of influent and energy consumption of wastewater treatment plants

Luxi Zou, Huaibo Li, Shuo Wang, Kaikai Zheng, Yan Wang, Guocheng Du, Ji Li

Frontiers of Environmental Science & Engineering 2019, Volume 13, Issue 6, doi: 10.1007/s11783-019-1167-7

Abstract: Poor biodegradability and insufficient carbon source are discovered from influent. Influent indices presented positively normal distribution or skewed distribution. Average energy consumption of WWTPs in Taihu Basin was as high as 0.458 kWh/m3. Energy consumption increases with the increase in influent volume and COD reduction. The total energy consumption decreases with the NH3-N reduction. The water quality and energy consumption of wastewater treatment plants (WWTPs) in Taihu Basin were evaluated on the basis of the operation data from 204 municipal WWTPs in the basin by using various statistical methods. The influent ammonia nitrogen (NH3-N) and total nitrogen (TN) of WWTPs in Taihu Basin showed normal distribution, whereas chemical oxygen demand (COD), biochemical oxygen demand (BOD5), suspended solid (SS), and total phosphorus (TP) showed positively skewed distribution. The influent BOD5/COD was 0.4%–0.6%, only 39.2% SS/BOD5 exceeded the standard by 36.3%, the average BOD5/TN was 3.82, and the probability of influent BOD5/TP>20 was 82.8%. The average energy consumption of WWTPs in Taihu Basin in 2017 was 0.458 kWh/m3. The specific energy consumption of WWTPs with a daily treatment capacity of more than 5 × 104 m3 in Taihu Basin was stable at 0.33 kWh/m3. A power function relationship was observed between the reduction in COD and NH3-N and the specific energy consumption of pollutant reduction, and the higher the pollutant reduction is, the lower the specific energy consumption of pollutant reduction presents. In addition, a linear relationship existed between the energy consumption of WWTPs and the specific energy consumption of influent volume and pollutant reduction. Therefore, upgrading and operation with less energy consumption of WWTPs is imperative and the suggestions for Taihu WWTPs based on stringent discharge standard are proposed in detail.

Keywords： treatment plant     Influent characteristics     Energy consumption evaluation     Specific energy consumption     SPSS correlation    

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Correlation analysis of couple optical paths for micro stereovision with stereo light microscope

WANG Yuezong, LI Desheng, YU Yaping

Frontiers of Mechanical Engineering 2007, Volume 2, Issue 3,   Pages 288-292 doi: 10.1007/s11465-007-0050-6

Abstract: In this paper, a correlation function is proposed to describe the coupling intension between the coupleExperiments show that the correlation of the optical paths of a common main objective of stereo lightthat of a G-SLM, and the error must be considered when a pinhole imaging model is used to analyze its correlation

Keywords： intension     micromanipulation     correlation function     objective     quantified    

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Water-dispersible nano-pollutions reshape microbial metabolism in type-specific manners: A metabolic and bacteriological investigation in

Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 9, doi: 10.1007/s11783-022-1548-1

Abstract:

• Water-dispersible nano-pollutions exhibit type-specific toxic effects on E. coli.

Keywords： Nano-toxicity     Nano-plastics     Quantum dots     Microbial metabolite     Metabolic dysregulation    

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The Characteristic of Spectrum and Self-correlation of Some Boolean Fuctions Linearly Equivalent to Specific

Yang Rui,Zeng Bensheng,Li Shiqu

Strategic Study of CAE 2005, Volume 7, Issue 11,   Pages 60-65

Abstract: obtained a sufficient and necessary condition about a Boolean function linearly equivalent to some m order correlation-immuneMoreover, it showed an example,in which a given Boolean function, that is not correlation-immuned anddoes not satisfy the propagation criterion can be constructed into a correlation-immuned Boolean function

Keywords： linear equivalence     Walsh cycle spectrum     self-correlation function     correlation-immunity     propagation criterion    

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A new heat transfer correlation for supercritical fluids

Yanhua YANG, Xu CHENG, Shanfang HUANG

Frontiers in Energy 2009, Volume 3, Issue 2,   Pages 226-232 doi: 10.1007/s11708-009-0022-0

Abstract: Emphasis is put on the simplicity of the correlation structure and its explicit coupling with physicalThe new correlation structure excludes direct dependence of heat transfer coefficient on wall surfacerequired for the selection of both the dimensionless parameters implemented into the heat transfer correlationComparison of various heat transfer correlations with the selected test data shows that the new correlation

Keywords： super critical fluids     heat transfer     circular tubes     prediction method    

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Seismic ground motion analysis of Shanghai Pudong Airport site considering the effects of spatial correlation

JIANG Tong, CHEN Laiyun, XING Hailing, L? Xilin

Frontiers of Structural and Civil Engineering 2007, Volume 1, Issue 4,   Pages 430-435 doi: 10.1007/s11709-007-0058-3

Abstract: The spatial correlation of seismic ground motion, as well as the amplification of soft alluvium and theFor indicating the effect of the spatial correlation of input motions, the horizontal uniform inputs,

Keywords： surface ground     horizontal uniform     Finally     seismic ground     correlative seismic    

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Reliability analysis on civil engineering project based on integrated adaptive simulation annealing and gray correlation

Xiao-ping BAI,Ya-nan LIU

Frontiers of Structural and Civil Engineering 2016, Volume 10, Issue 4,   Pages 462-471 doi: 10.1007/s11709-016-0361-y

Abstract: analysis of the four quality influence factors in the construction engineering, a method based on gray correlation

Keywords： civil engineering     dynamic reliability     grey relational degree     adaptive simulated annealing algorithm    

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Title Author Date Type Operation

Time-dependent metabolomics uncover dynamic metabolic adaptions in MCF-7 cells exposed to bisphenol A

Journal Article

Epigenetic dysregulation in hepatocellular carcinoma: focus on polycomb group proteins

Sandy Leung-Kuen Au, Irene Oi-Lin Ng, Chun-Ming Wong

Journal Article

Digital image correlation-based structural state detection through deep learning

Journal Article

Diagnosis method based on wavelet coefficient scale relativity correlation dimension for fault

GU Junjie, TIAN Jin, PENG Xuezhi

Journal Article

Reliability analysis of urban gas transmission and distribution system based on FMEA and correlation

Su LI,Weiguo ZHOU

Journal Article

Measurement and correlation of the solid-liquid equilibrium of 2-(

Yanhong SUN, Zhiyong LI, Chuang XIE, Wei CHEN, Cui ZHANG

Journal Article

Deformation field and crack analyses of concrete using digital image correlation method

Yijie HUANG, Xujia HE, Qing WANG, Jianzhuang XIAO

Journal Article

Free radical scavenging window of infertile patients with polycystic ovary syndrome: correlation with

Bo Huang, Zhou Li, Xinling Ren, Jihui Ai, Lixia Zhu, Lei Jin

Journal Article

Characteristic and correlation analysis of influent and energy consumption of wastewater treatment plants

Luxi Zou, Huaibo Li, Shuo Wang, Kaikai Zheng, Yan Wang, Guocheng Du, Ji Li

Journal Article

Correlation analysis of couple optical paths for micro stereovision with stereo light microscope

WANG Yuezong, LI Desheng, YU Yaping

Journal Article

Water-dispersible nano-pollutions reshape microbial metabolism in type-specific manners: A metabolic and bacteriological investigation in

Journal Article

The Characteristic of Spectrum and Self-correlation of Some Boolean Fuctions Linearly Equivalent to Specific

Yang Rui,Zeng Bensheng,Li Shiqu

Journal Article

A new heat transfer correlation for supercritical fluids

Yanhua YANG, Xu CHENG, Shanfang HUANG

Journal Article

Seismic ground motion analysis of Shanghai Pudong Airport site considering the effects of spatial correlation

JIANG Tong, CHEN Laiyun, XING Hailing, L? Xilin

Journal Article

Reliability analysis on civil engineering project based on integrated adaptive simulation annealing and gray correlation

Xiao-ping BAI,Ya-nan LIU

Journal Article